Jules wakes up naked in the woods with blood in her mouth and wanders over to a campsite. There are human limbs scattered around so she piles them and burns them. A cop drives up and approaches her so she starts crying over what's left of the corpses and claims a wolf attacked them. When he turns his back, she smashes his head open with a log. She goes to see Sheriff Forbes to ask about the investigation into Mason. Forbes fobs her off.
At the Salvatore's, a shirtless Stefan surprises Elena and they make out. She wants to be together all the time. He worries about Elijah's plans for her and then drinks down his diluted verbane. Downstairs, Rose tells Damon that she's more than 500 and ready to die. He tries giving her some blood to help heal her but her scabs only get worse. Elena walks in and worries about Stefan. Damon asks her to play nurse to Rose while he works on something with his brother. He admits that Rose will die. "We come, we go. The sooner she dies, the better," he says. Elena takes her up to Damon's bedroom and looks around, surprised to see the room nearly empty except for his copy of "Gone With The Wind." Rose quizzes her about Elijah and assumes that she really is determined to die. The vampire starts hallucinating and then asks for more blood. She chokes when she drinks it and then jumps her. Elena yells that she isn't Katherine and the vamp snaps out of it. She calms down for a minute and then runs off. Elena finds her in the basement drinking blood and Rose starts to think she's Katherine again. When Rose jumps on her, Elena pulls down a drape and the sun burns her. Then Elena digs her fingernails into her scabs until she collapses. She barricades herself into a room.
Stefan meets Alaric at the bar and they talk about a cure for Rose and then he digs for info on Klaus. He gets Isabella's number and calls her, leaving a message. Damon shows up and his brother grabs him before he can go after Jules. Stefan takes a call as Damon confronts Jules. They exchange threats. He offers not to kill her if she'll tell him how to cure a wolf bite. "Take a stake and drive it through her heart," she says, walking out.
At school, Caroline tells Tyler how great he was for handling his transformation without hurting anyone. He thanks her for her help. She's awkward and tells him that a bite from a wolf can kill a vampire. He wants more information but Matt shows up so Tyler heads off. Caroline assures him nothing is going on between her and Tyler. He mutters and then kisses her. She pulls away. He follows her inside and asks her what happened. She says she loves him. He's confused. She disappears to avoid explaining.
Damon goes home and finds Elena walking around with a stake in her hand. Meanwhile, Rose is on the street puking behind a dumpster. A man approaches and she bites him. The cops soon arrive and call Damon in. He soon finds Rose biting some woman. He jumps on her and tries to calm her. She's disoriented, cries and begs for this to stop. Damon carries her home and puts her to bed. She soon wakes up and apologizes. Rose begins talking about the pleasure of killing. She tells Elena that Damon wants to care but he runs away when he does. She's still haunted by memories of being human. As she screams in pain, Damon sends Elena out. He cradles Rose and gets her to sleep. She dreams of her life as a person. Damon is there. They enjoy the sun and she misses being human. He doesn't think it's all it's cracked up to be. As he holds her, she tells him she's not afraid of dying anymore. Once her body is relaxed, he puts the stake through her heart and cries. He loads her body into the car and drives her to the sheriff, though he insists on burying the body himself. When he gets home, Elena is waiting for him. He claims he didn't care about Rose but she can see he's lying. "It was supposed to be me," he says, ordering her to go home. She gives him a hug. As she leaves, she runs into Stefan and he tells her that he called Isabelle. Uncle John suddenly walks out of the shadows.
When Caroline gets home, Tyler is waiting for her. He wants to know why she would risk her life by helping him. When she becomes defensive, he kisses her. Eventually, she pulls away and tells him he can't do that. "Everyone needs to stop kissing me," she says, running inside. He goes to meet Jules at the bar. She tells him that she knew about Mason and she knows he's a werewolf too. She's shocked to discover he's brand new at this and offers to help him. He's not happy when she tells him that Caroline killed his uncle and the town is crawling with vampires.
A woman drives up and stops as she approaches a body in the middle of the road. She gets out to see it. It's Damon. He tells her that he's lost and drunk. As he swigs from his flask, he rants about how he can never be good or adopt a puppy. He can never be who 'she' wants him to be. He debates killing her but he has to because he misses being human so much. He tries to let her go but then lunges at her and kills her.
Cryptic commentary: It was a long wait. Was it full of surprises? Not really, although Damon's "Gone With The Wind" fetish was both spooky and funny. There were some more good moments between Tyler and Caroline but the real kicker of the episode was Rose's deathbed scene with Damon that gave them both a lot more soul than they usually show. It was especially potent coming after the whole heroin withdrawal style disintegration she went through.