Actress L. Scott Caldwell, who played Rose Nadler on the hit series, "Lost," will be making a guest appearance on Grey's Anatomy. The episode, in which she will play the wife of a patient participating in Derek Shepherd's (Patrick Dempsey) Alzheimer's clinical trial, is slated to air on February 23. L. Scott Caldwell has also done a guest spot on "The Secret Life of the American Teenager" since "Lost" wrapped up for good.
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