Chad Duell ("Wizards of Waverly Place," "Suite Life on Deck") will replace Garret beginning April 20.
In a statement, ABC declared, "The continuing storyline will have viewers on the edge in the weeks leading up to May sweeps as Michael and his father frantically try to hide the truth that he murdered his stepmother Claudia."
They added, "We want to thank Drew Garrett for his time with General Hospital and wish him well in all his future endeavors."
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