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Will Greens and Frankie Die?

Julia arrives with the crash cart just as Angie loses Frankie's heartbeat! The orderly tries to wheel Greenlee away but Kendall and Greens won't let him go. Finally they get a heartbeat. The orderly insists that they leave now. Angie orders more meds from Julia and another doctor orders an eco-cardiogram. Angie and the other doctor, Nick, confer and discover that the cardiac arrest may not have been caused by the anti-toxin they've been giving Frankie. He suggests letting Frankie build his strength and try another dose in a few days. Julia brings Angie some new research and asks what caused Frankie's reaction. Angie admits she doesn't know and continues on to talk with Joe and the lab techs. Julia follows. Angie tells them about the latest cardiac event and Joe asks the others to leave so he can speak privately with Angie. Joe tells her again that she needs to recuse herself from Frankie's case; Angie refuses. "Oh, God, I almost killed him," she cries. Joe hugs Angie, reminding her that she saved her son's life during the arrest. Joe invites the others back in and Angie goes over Frankie's latest stats - his kidneys and liver are beginning to shut down and his blood counts are off, too. Julia asks why Greenlee and Frankie are reacting differently but Angie doesn't know.

Aidan is freaking out in Greenlee's hospital room when Zach walks in. He and Zach find Greenlee and Kendall on the way to Greens' test; they tell the guys about Frankie's cardiac arrest. Greenlee believes it is the treatment that Joe, Angie and the CDC researchers have developed and is very scared that the same thing will happen to her. Aidan offers to take her to the test. Kendall stays with Zach, telling him about Greenlee's fears. Kendall and Zach return to Greenlee's room as she is returned from the test. Kendall tries to talk books with Greens to distract her; she tells Kendall to get to work on the book so the edits are ready on time. Zach agrees to stay with Greens and Kendall leaves. Greenlee begins to cry. Zach hugs her and lets her sob. She asks Zach to tell her the truth about her condition and Frankie's. Zach tells her to ask the doctors herself. Dr. Nick comes in and asks Zach to leave. He checks Greenlee's lungs and heart, asking how she is. Greenlee admits to being tired and having a sore throat from the tubes; she asks him what is going on with Frankie. Nick says her condition isn't the same as Frankie's, so she may not react the way he has. A nurse delivers new blood-work. Nick goes to find Angie. Greens is sleeping when Nick and Angie return. Greenlee's kidneys are decreasing their function and her enzymes are abnormal. Nick suggests surgery but Angie says she is too weak to survive it. Nick says they have to risk it because Greenlee is deteriorating faster than Frankie is! As they talk Jack and Aidan listen in. Angie takes them down the hall and sends Nick to check on Frankie. She tells Jack and Aidan that Greenlee's organs are shutting down. "The toxin has mutated," Angie explains and says they have developed a new treatment that may or may not have caused Frankie's heart attack. Angie is paged back to the lab. Jack and Aidan watch Greenlee through the window. Julia comes in, telling them that Greenlee is resting. She opens her eyes and smiles at Jack; Julia tells him to go see his daughter. Aidan gives Jack and Greenlee some time alone. Jack tries to hold back his tears but can't. "Montgomery's don't give up easily, so don't you," Jack says as Greenlee goes to sleep.

Angie and Joe are trying to figure out the dangers of injecting Greenlee with the same anti-toxin they gave Frankie. Angie says she thinks they'll both die without the injection; Joe tells her to go with her gut. She and Joe talk to Aidan and Jack, telling them they have adjusted the treatment but they still aren't sure how Greens will react. Angie says she will die if they don't do something now. Zach listens to them. "When I tell you this is her only chance, I mean it," Angie says. Jack and Aidan go to tell Greenlee about the treatment. She doesn't like her choices any better than the men do. Greens asks them to get Zach! Jack and Aidan let Zach in; Aidan is a little annoyed, not because of Greenlee's request but because he can't help her. Jack calls Lily to check in and then sits with Aidan to wait. Kendall returns.

Frankie Refuses Treatment!

Joe is talking to a couple of the CDC researchers about possible treatments when Angie walks up to them. She tells the researchers that even with the unknowns they should go ahead with experimental treatments because Frankie and Greens don't have much time left. Angie goes to check on Frankie; he asks about his treatment and Angie tells him about the experimental treatment. Joe calls to Angie that the serum is ready and Angie injects Frankie. Frankie begins to dream. In the dream, Angie tells him that Jesse really is alive and Jesse stands by Angie at his bedside. Frankie wakes and pulls the needles and tubes from his arms! Angie rushes in, tells him to calm down and let the medicine work. She returns to the hall and prays to Jesse to give her strength.

Annie Can't Give Richie A Transplant!

Meanwhile at the hospital, Kendall is making calls to anyone and everyone, asking them to come to the hospital to donate blood for Greenlee and Frankie. Zach asks Joe what is going on with the patients and Joe says the virus is mutating and their efforts aren't working!

In Frankie's room, Jesse begins to cry. He apologizes to Frankie for leaving when Frankie was a kid and says he would do anything to fight this disease for his child. "I love you, I never stopped," Jesse says as Frankie opens his eyes! Jesse hurries out of the room. Frankie, whose vision is blurred, wonders if he really saw his father. Joe comes in and Frankie tries to tell him what he saw but can't speak. He writes "Dad was here" on Joe's medical chart! Angie walks in and Joe shows her the note; she is shocked and believes Frankie is hallucinating. Frankie opens his eyes and whispers that Jesse was definitely there. "It was real, Mom," he says before dropping back into unconsciousness. Joe and Angie step into the hall. Angie tells Joe that she can't lose another family member in this hospital. Angie returns to Frankie's bedside to make a few calls to the CDC and other researchers she knows, trying to hurry the research along. Angie returns to Frankie's side, holds his hand and says, "Jesse I need you now more than ever." Tad walks in and tells Angie to take a break. They sit in the hall for a while; Angie tells Tad about the illness and the research. Then she tells him about Frankie's "hallucination"; Tad says he's seen Jesse, too, with Jenny! "He showed me the way home. That's what he's doing for Frankie," Tad says reassuringly. Jesse returns to Frankie's bedside and promises not to leave his son again.

Zach runs into Joe, who says they don't have all the answers yet but they are getting close. Zach returns to Greenlee's room and watches through the window with Aidan for a few moments. Zach tells Aidan that she won't give up easily. "She's strong, she's not gonna quit," Zach says, asking Aidan not to quit on Greenlee, either. They turn back to Greenlee, who begins seizing! Julia is there and tells them to get Angie, quickly!

Angie and Joe rush into Greenlee's room and manage to stop the seizure. Angie says Greenlee can't take much more; she takes the family into the hall and tells them all that she doesn't know how to stop Greenlee's or Frankie's illness. Zach and Aidan fill Jack in about Sylvester. Angie hurries off to the research lab. Jack calls Erica, upset about Greenlee but needing a distraction. He tells her to take care of the stock problem they discussed at dinner earlier that night. Zach and Kendall go down the hall; she is almost asleep standing up and Zach tells her to go home. Kendall refuses, saying she has to be with Greenlee now. She returns to Greenlee's room. Aidan returns to Greenlee's bedside and holds her hand. Ryan arrives.

Joe finds Angie back at Frankie's bedside and tells her that she shouldn't continue treating Frankie because of the conflict of interest clause at the hospital. Because she is Frankie's mom, the hospital would like her to back away! Angie, crying, tells Joe to make an exception to the rule. "I didn't come home just to see my son die," she says. Joe agrees not to remove Angie and she returns to watch Frankie through the window. Angie thinks she sees someone lurking down the hall but can't see anything so she returns to Frankie's side. Around the corner, Jesse is watching!

Jesse's Back In Town!

At Fusion the medics arrive and get to work on Greenlee. They discover an airway obstruction that they can't get rid of, put an oxygen mask on her and hurry away. Kendall finally answers Greenlee's ringing phone and tells Aidan about Greenlee's breathing troubles. She tells him to meet them at the hospital.

Zach, Aidan and Angie are waiting when the medics wheel Greenlee in. Julia hurries into the room, too. Kendall repeats, "She has to be fine," over and over and Zach drags her from the room. He tells Kendall she has to have a blood test because of the time she spent in the woods. She agrees to the test. She and Zach are walking back when he remembers the root; he leaves to check something else out. Kendall returns and Angie tells her that Greenlee is stabilized for now. Angie continues on to Julia who shows her Sylvester's files. Angie asks about the CDC and learns that they haven't returned the hospital's calls yet. Angie returns to Greenlee. Joe walks up and Julia tells him that the CDC is still not on their way. Kendall asks if she can do anything and Joe tells her to get Jack to the hospital quickly. Kendall goes off. Joe then turns to Aidan and tells him that the hospital is going to need blood - and lots of it - if Greenlee's and Frankie's conditions don't improve. Kendall tries calling Jack several times but he doesn't answer his phone.